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American Journal of Epidemiology Advance Access first published online on October 28, 2008
This version published online on November 6, 2008
American Journal of Epidemiology, doi:10.1093/aje/kwn290
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American Journal of Epidemiology © The Author 2008. Published by the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org.

Invited Commentary: Residential Segregation and Health—The Complexity of Modeling Separate Social Contexts

Dolores Acevedo-Garcia and Theresa L. Osypuk

Correspondence to Dr. Dolores Acevedo-Garcia, Department of Society, Human Development and Health, Harvard School of Public Health, 766 Huntington Avenue, Boston, MA 02115 (e-mail: dacevedo{at}hsph.harvard.edu).

Received for publication July 28, 2008. Accepted for publication August 14, 2008.

When researching racial disparities in health, residential segregation cannot be ignored. Because of segregation, contextual differences by race are so pronounced that ignoring them may lead to misestimating the effect of individual-level factors. However, given the stark racial separation of social contexts, researching how residential segregation and neighborhood inequality contribute to racial health disparities remains methodologically challenging. Estimating the contribution of neighborhood effects to health disparities would require overlap in the racial distributions of neighborhood environment, for example, in the distributions of neighborhood poverty. Because of segregation, though, the extent of such overlap is extremely restricted. Previous analyses of the 2000 US Census found, on average, only a 24% overlap between the distribution of neighborhood poverty for black children and that for white children in metropolitan areas. Propensity score methods may be 1 useful tool for addressing limited overlap or exchangeability. However, as shown by their application to the segregation and health relation, their use should be informed by a sound conceptualization of the scale of the social exposure of interest, the hypothesized pathways between the exposure and the health outcome, and possible unmeasured confounders.

African Americans; infant mortality; residence characteristics

Reference 24 has been updated.


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