American Journal of Epidemiology Advance Access first published online on August 13, 2008
This version published online on September 22, 2008
American Journal of Epidemiology, doi:10.1093/aje/kwn189
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Original Contribution |
Recreational Physical Activity and the Risk of Preeclampsia: A Prospective Cohort of Norwegian Women
Correspondence to Dr. Per Magnus, Division of Epidemiology, Norwegian Institute of Public Health, P.O Box 4404, Nydalen, 0403 Oslo, Norway (e-mail: per.magnus{at}fhi.no).
Received for publication January 4, 2008. Accepted for publication May 30, 2008.
Previous case-control studies suggest that recreational physical activity protects against preeclampsia. Using a prospective design, the authors estimated the risk of preeclampsia for pregnant women according to level of physical activity, taking other variables that influence risk into consideration. The data set comprised 59,573 pregnancies from the Norwegian Mother and Child Cohort Study (1999–2006). Information on physical activity and other exposures was extracted from questionnaire responses given in pregnancy weeks 14–22, whereas diagnosis of preeclampsia was retrieved from the Medical Birth Registry of Norway. Estimation and confounder control was performed with multiple logistic regression. About 24% of pregnant women reported no physical activity, and 7% reported more than 25 such activities per month. The adjusted odds ratio was 0.79 (95% confidence interval: 0.65, 0.96) for preeclampsia when comparing women who exercised 25 times or more per month with inactive women. The association appeared strongest among women whose body mass index was less than 25 kg/m2 and was absent among women whose body mass index was higher than 30 kg/m2. These results suggest that the preventive effect of recreational physical activity during pregnancy may be more limited than has been shown in case-control studies and may apply to nonobese women only.
body mass index; cohort studies; exercise; pre-eclampsia; pregnancy
Abbreviations: BMI, body mass index; MoBa, Norwegian Mother and Child Cohort Study
The author detected a typo on page 953, 37 weeks should be 34 weeks
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  P.-J. Chang, L.-C. Chu, W.-S. Hsieh, Y.-L. Chuang, S.-J. Lin, and P.-C. Chen Working hours and risk of gestational hypertension and pre-eclampsia Occup. Med., August 21, 2009; (2009) kqp119v1. [Abstract] [Full Text] [PDF]
|
|