Skip Navigation



American Journal of Epidemiology Advance Access published online on June 10, 2008
American Journal of Epidemiology, doi:10.1093/aje/kwn137
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
168/3/321    most recent
kwn137v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Kumarapeli, V.
Right arrow Articles by Dodampahala, S. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kumarapeli, V.
Right arrow Articles by Dodampahala, S. H.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

American Journal of Epidemiology © The Author 2008. Published by the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org.

Practice of Epidemiology

A Simple Screening Approach for Assessing Community Prevalence and Phenotype of Polycystic Ovary Syndrome in a Semiurban Population in Sri Lanka

V. Kumarapeli1, R. de A. Seneviratne2, C. N. Wijeyaratne3, R. M. S. C. Yapa4 and S. H. Dodampahala3

1 Public Health Complex, Ministry of Health, Colombo, Sri Lanka
2 Department of Community Medicine, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka
3 Department of Obstetrics and Gynecology, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka
4 De Zoysa Hospital for Women, Colombo, Sri Lanka

Correspondence to Dr. V. Kumarapeli, Department of Population and International Health, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115 (e-mail: vindyalk{at}yahoo.com, vkumarap{at}hsph.harvard.edu).

Received for publication October 29, 2007. Accepted for publication April 28, 2008.

In most of South Asia, prevalences and phenotypes of polycystic ovary syndrome (PCOS) among women in the community are unknown. The authors aimed to estimate prevalence and phenotype in a community setting in Sri Lanka and to test a valid, feasible screening approach to early diagnosis. A community-based, cross-sectional study was carried out in 2005–2006. A random sample of 3,030 women aged 15–39 years was selected by cluster sampling proportionate to population size. An interviewer-administered questionnaire was utilized to screen for "probable cases" of PCOS based on menstrual history and clinical manifestations of hyperandrogenism. Selected "probable cases" underwent clinical, biochemical, and ovarian ultrasound assessment. The response rate was 96.2% (n = 2,915). A total of 220 (7.5%) "probable cases" were identified: 209 women with oligo/amenorrhea (95%) and 11 women with hirsutism (5%). Further evaluation of the 220 probable cases confirmed 164 newly diagnosed cases of PCOS based on the 2003 Rotterdam diagnostic criteria. With 19 previously diagnosed cases already present, total prevalence was 6.3% (95% confidence interval: 5.9, 6.8). Of the women with "oligo/amenorrhea and/or hirsutism," 91.1% were confirmed to have PCOS; 99.4% of women with "regular cycles in the absence of clinical hyperandrogenism" were confirmed as normal. The most common phenotypes of PCOS were oligo/amenorrhea and polycystic ovaries (91.4%) and oligo/amenorrhea and hirsutism (48.3%).

mass screening; polycystic ovary syndrome; Sri Lanka

Abbreviations: FG, Ferriman and Gallway; PCOS, polycystic ovary syndrome


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J. Clin. Endocrinol. Metab.Home page
E. A. M. Kuijper, J. M. Vink, C. B. Lambalk, and D. I. Boomsma
Prevalence of Polycystic Ovary Syndrome in Women from Opposite-Sex Twin Pairs
J. Clin. Endocrinol. Metab., June 1, 2009; 94(6): 1987 - 1990.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.