American Journal of Epidemiology Advance Access published online on February 22, 2008
American Journal of Epidemiology, doi:10.1093/aje/kwn018
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American Journal of Epidemiology © The Author 2008. Published by the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org.
Letter to the Editor |
RE: "PLASMA FLUORESCENT OXIDATION PRODUCTS AS POTENTIAL MARKERS OF OXIDATIVE STRESS FOR EPIDEMIOLOGIC STUDIES"
1 Department of Surgery, Isala Clinics, Zwolle 8023AN, The Netherlands
2 Department of Internal Medicine, University Medical Center Groningen, 9700 RB Groningen, The Netherlands
3 Department of Surgery, University Medical Center Groningen, 9700 RB Groningen, The Netherlands
(e-mail: r.meerwaldt@isala.nl)
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In two recent studies, Wu et al. showed that fasting plasma levels of fluorescent oxidation products are markers of oxidative stress (1) and independently predict coronary heart disease in men (2). The authors concluded that this fluorescent assay may become a useful global marker for epidemiologic studies. As mentioned by Wu et al., "this method has not been widely used [as it may be]