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American Journal of Epidemiology Advance Access published online on January 29, 2008
American Journal of Epidemiology, doi:10.1093/aje/kwm358
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American Journal of Epidemiology © The Author 2008. Published by the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org.

Pischon et al. Respond to "Variable Selection versus Shrinkage in Control of Confounders"

Tobias Pischon, Matthias B. Schulze, Dagmar Drogan and Heiner Boeing

From the Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany

Correspondence to Dr. Tobias Pischon, Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Arthur-Scheunert-Allee 114–116, 14558 Nuthetal, Germany (e-mail: pischon@dife.de).

Received for publication October 24, 2007. Accepted for publication November 7, 2007.

The first 10% of the full text of this article appears below.

We read with great interest Dr. Greenland's invited commentary (1) about variable selection to control for confounding in observational studies. We agree with Dr. Greenland that the identification of confounders should be based primarily on background knowledge and not on significance testing. However, our proposed method (2) is not meant primarily as . . . [Full Text of this Article]


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