Dietary Patterns and Risk of Incident Gastric Adenocarcinoma

doi:10.1093/aje/kwm294

American Journal of Epidemiology Advance Access published online on November 28, 2007
American Journal of Epidemiology, doi:10.1093/aje/kwm294

This Article

	Full Text
	FREE Full Text (PDF)
	All Versions of this Article: 167/3/295 most recent kwm294v1
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Add to My Personal Archive
	Download to citation manager
	Request Permissions
	Disclaimer

Google Scholar

	Articles by Campbell, P. T.
	Articles by Kreiger, N.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Campbell, P. T.
	Articles by Kreiger, N.

Social Bookmarking

	What's this?

American Journal of Epidemiology © The Author 2007. Published by the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org.

Original Contribution

Dietary Patterns and Risk of Incident Gastric Adenocarcinoma

Peter T. Campbell¹^,2, Margaret Sloan¹ and Nancy Kreiger¹^,3^,4

¹ Division of Preventive Oncology, Cancer Care Ontario, Toronto, Ontario, Canada
² Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, WA
³ Department of Public Health Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
⁴ Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada

Correspondence to Dr. Nancy Kreiger, Division of Preventive Oncology, Cancer Care Ontario, 620 University Avenue, Toronto, Ontario, Canada M5G 2L7 (e-mail: nancy.kreiger{at}cancercare.on.ca).

Received for publication April 9, 2007. Accepted for publication September 17, 2007.

Few studies have assessed the relation between dietary patternsand gastric adenocarcinoma risk, yet this approach has advantagesover single-nutrient analysis, including the ability to reflecteating patterns in populations and ease of implementing dietaryrecommendations. The authors evaluated associations betweendietary patterns, a food index score, and incident gastric cancerrisk in a Canadian study of 1,169 cases and 2,332 controls (1995–1997).Dietary patterns were assessed via factor analysis applied toa food frequency questionnaire. A food index score was derivedbased on risk factors for gastric cancer. A multivariable-adjustedprudent dietary pattern was associated with decreased risk ofgastric cancer in women (odds ratio (OR) = 0.58, 95% confidenceinterval (CI): 0.37, 0.92); a Western dietary pattern was associatedwith increased risk in women (OR = 1.86, 95% CI: 1.20, 2.89)and men (OR = 1.44, 95% CI: 1.03, 2.02). The food index scorewas associated with decreased risk among women (OR = 0.40, 95%CI: 0.27, 0.59) and men (OR = 0.63, 95% CI: 0.45, 0.88). Dietarypatterns especially characterized by Western features (softdrinks, processed meats, refined grains, and sugars) were associatedwith increased risk of gastric adenocarcinoma, whereas dietarypatterns characterized by increased consumption of fruits, vegetables,and fish were associated with lessened risk.

diet; nutrition surveys; risk factors; stomach neoplasms

Abbreviations: CI, confidence interval; FFQ, food frequency questionnaire; OR, odds ratio

Add to CiteULike CiteULike Add to Connotea Connotea Add to Del.icio.us Del.icio.us What's this?

This article has been cited by other articles:

P. Bertuccio, V. Edefonti, F. Bravi, M. Ferraroni, C. Pelucchi, E. Negri, A. Decarli, and C. La Vecchia
Nutrient Dietary Patterns and Gastric Cancer Risk in Italy
Cancer Epidemiol. Biomarkers Prev., November 1, 2009; 18(11): 2882 - 2886.
[Abstract] [Full Text] [PDF]