American Journal of Epidemiology Advance Access published online on June 12, 2007
American Journal of Epidemiology, doi:10.1093/aje/kwm138
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American Journal of Epidemiology Copyright © 2007 by the Johns Hopkins Bloomberg School of Public Health All rights reserved; printed in U.S.A.
Østerdal et al. Respond to "Identifying Women with Hypertension during Pregnancy"
1 Maternal Nutrition Group, Danish Epidemiology Science Centre, Statens Serum Institut, Copenhagen, Denmark
2 Department of Obstetrics and Gynecology, H:S Hvidovre Hospital, University of Copenhagen, Hvidovre, Denmark
3 Ultrasound Clinic, Juliane Marie Center, H:S Rigshospitalet, Copenhagen, Denmark
4 Department of Epidemiology, Institute of Public Health, University of Aarhus, Aarhus, Denmark
Correspondence to Marie Louise Østerdal, Maternal Nutrition Group, Danish Epidemiology Science Centre, Statens Serum Institut, Artillerivej 5, DF-2300 Copenhagen S, Denmark (e-mail: mae@ssi.dk).
Received for publication March 2, 2007. Accepted for publication April 4, 2007.
| The first 10% of the full text of this article appears below. |
We appreciate the opportunity to comment on Dr. Callaghan's commentary (1) on our original paper published in this issue (2). Dr. Callaghan raises pivotal points regarding the highly complex nature of preeclampsia.
Complexity exists on at least two different levels. First, there is variation in the time of onset, severity, and type of clinical presentation. Because a particular presentation may have particular etiologic implications, this variation should be captured in the data collection, when we want to study both the etiology