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American Journal of Epidemiology Advance Access published online on April 12, 2007
American Journal of Epidemiology, doi:10.1093/aje/kwm077
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American Journal of Epidemiology Copyright © 2007 by the Johns Hopkins Bloomberg School of Public Health All rights reserved; printed in U.S.A.

Response to Invited Commentary

Tyas et al. Respond to "Predictors of Rate of Change in Disease Progression"

Suzanne L. Tyas1,2, Juan Carlos Salazar3, David A. Snowdon4,5, Mark F. Desrosiers5, Kathryn P. Riley5,6, Marta S. Mendiondo5,7 and Richard J. Kryscio5,7,8

1 Department of Health Studies and Gerontology, University of Waterloo, Waterloo, Ontario, Canada
2 Division of Behavioural Neuroscience, Department of Psychology, University of Waterloo, Waterloo, Ontario, Canada
3 School of Statistics, National University of Colombia at Medellín, Medellín, Colombia
4 Department of Neurology, University of Kentucky, Lexington, KY
5 Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY
6 Department of Preventive Medicine and Environmental Health, University of Kentucky, Lexington, KY
7 Department of Biostatistics, University of Kentucky, Lexington, KY
8 Department of Statistics, University of Kentucky, Lexington, KY

Received for publication January 31, 2007. Accepted for publication February 8, 2007.

The first 10% of the full text of this article appears below.

In her commentary (1), Dr. Glymour describes four phenomena leading to a spurious association between risk factors for disease onset and the rate of disease progression. . . . [Full Text of this Article]


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