Skip Navigation



American Journal of Epidemiology Advance Access published online on September 21, 2006
American Journal of Epidemiology, doi:10.1093/aje/kwj324
This Article
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
164/11/1085    most recent
kwj324v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Kesse, E.
Right arrow Articles by Boutron-Ruault, M. C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kesse, E.
Right arrow Articles by Boutron-Ruault, M. C.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

American Journal of Epidemiology Copyright © 2006 by the Johns Hopkins Bloomberg School of Public Health All rights reserved; printed in U.S.A.
Received September 27, 2005
Accepted April 28, 2006

ORIGINAL CONTRIBUTIONS

Dietary Patterns and Risk of Colorectal Tumors: A Cohort of French Women of the National Education System (E3N)

E. Kesse 1, F. Clavel-Chapelon 1, and M. C. Boutron-Ruault 1 *

1 From the Inserm, ERI20, Equipe E3N, Institut Gustave Roussy, Villejuif Cedex, France

* To whom correspondence should be addressed.
M. C. Boutron-Ruault, E-mail: boutron{at}igr.fr


  Abstract

Little is known about the dietary patterns associated with colorectal tumors along the adenoma-carcinoma sequence. Scores for dietary patterns were obtained by factor analysis in women from the French cohort of the European Prospective Investigation into Cancer and Nutrition (1993-2000). Their association with colorectal tumors was investigated in 516 adenoma cases (175 high-risk adenomas) and 4,804 polyp-free women and in 172 colorectal cancer cases and 67,312 cancer-free women. The authors identified four dietary patterns: "healthy" (vegetables, fruit, yogurt, sea products, and olive oil); "Western" (potatoes, pizzas and pies, sandwiches, sweets, cakes, cheese, cereal products, processed meat, eggs, and butter); "drinker" (sandwiches, snacks, processed meat, and alcoholic beverages); and "meat eaters" (meat, poultry, and margarine). For quartile 4 versus quartile 1, an increased risk of adenoma was observed with high scores of the Western pattern (multivariate relative risk (RR) = 1.39, 95% confidence interval: 1.00, 1.94; ptrend = 0.03) and the drinker pattern (RR = 1.42, 95% confidence interval: 1.10, 1.83; ptrend = 0.01). The meat-eaters pattern was positively associated with colorectal cancer risk (for quartile 4 vs. quartile 1: RR = 1.58, 95% confidence interval: 0.98, 2.53; ptrend = 0.02). Dietary patterns that reflect a Western way of life are associated with a higher risk of colorectal tumors.

Keywords: adenoma; cohort studies; colorectal neoplasms; diet; risk; women.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Am. J. Clin. Nutr.Home page
A. Flood, T. Rastogi, E. Wirfalt, P. N Mitrou, J. Reedy, A. F Subar, V. Kipnis, T. Mouw, A. R Hollenbeck, M. Leitzmann, et al.
Dietary patterns as identified by factor analysis and colorectal cancer among middle-aged Americans
Am. J. Clinical Nutrition, July 1, 2008; 88(1): 176 - 184.
[Abstract] [Full Text] [PDF]

Home page
 JAMAHome page
J. A. Meyerhardt, D. Niedzwiecki, D. Hollis, L. B. Saltz, F. B. Hu, R. J. Mayer, H. Nelson, R. Whittom, A. Hantel, J. Thomas, et al.
Association of Dietary Patterns With Cancer Recurrence and Survival in Patients With Stage III Colon Cancer
JAMA, August 15, 2007; 298(7): 754 - 764.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.