Skip Navigation



American Journal of Epidemiology Advance Access published online on August 11, 2006
American Journal of Epidemiology, doi:10.1093/aje/kwj281
This Article
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
164/9/873    most recent
kwj281v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Cheng, Y. J.
Right arrow Articles by Venkat Narayan, K. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Cheng, Y. J.
Right arrow Articles by Venkat Narayan, K. M.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

American Journal of Epidemiology Copyright © 2006 by the Johns Hopkins Bloomberg School of Public Health All rights reserved; printed in U.S.A.
Received January 11, 2006
Accepted April 6, 2006

ORIGINAL CONTRIBUTIONS

Peripheral Insensate Neuropathy--A Tall Problem for US Adults?

Yiling J. Cheng 1 *, Edward W. Gregg 1, Henry S. Kahn 1, Desmond E. Williams 1, Nathalie De Rekeneire 1, and K. M. Venkat Narayan 1

1 From the Division of Diabetes Translation, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, US Department of Health and Human Services, Atlanta, GA

* To whom correspondence should be addressed.
Yiling J. Cheng, E-mail: ycc1{at}cdc.gov


  Abstract

The relation between height and lower extremity peripheral insensate neuropathy among persons with and without diabetes was examined by use of the 1999-2002 US National Health and Nutrition Examination Survey with 5,229 subjects aged 40 or more years. A monofilament was used to determine whether any of three areas on each foot were insensate. Peripheral insensate neuropathy was defined as the presence of one or more insensate areas. Its prevalence was nearly twice as high among persons with diabetes (21.2%) as among those without diabetes (11.5%; p < 0.001). Men (16.2%) had 1.7 times the prevalence of peripheral insensate neuropathy as did women (9.4%), but the difference was not significant after adjustment for height. Greater height was associated with increased peripheral insensate neuropathy prevalence among persons with and without diabetes (p < 0.001). This association was characterized by a sharp increase in prevalence among persons who were taller than 175.5 cm. Peripheral insensate neuropathy risk was significantly higher among those taller than 175.5 cm (adjusted odds ratio = 2.3, 95% confidence interval: 1.5, 3.5). The authors conclude that body height is an important correlate of peripheral insensate neuropathy. This association largely accounts for the difference in peripheral insensate neuropathy prevalence between men and women. Height may help health-care providers to identify persons at high risk of peripheral insensate neuropathy.

Keywords: aging; body composition; data collection; diabetes mellitus; peripheral nervous system diseases.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Diabetes CareHome page
D. Ziegler, W. Rathmann, T. Dickhaus, C. Meisinger, A. Mielck, and for the KORA Study Group
Prevalence of Polyneuropathy in Pre-Diabetes and Diabetes Is Associated With Abdominal Obesity and Macroangiopathy: The MONICA/KORA Augsburg Surveys S2 and S3
Diabetes Care, March 1, 2008; 31(3): 464 - 469.
[Abstract] [Full Text] [PDF]

Home page
 Diabetes CareHome page
M. Tao, M. A. McDowell, S. H. Saydah, and M. S. Eberhardt
Relationship of Polyunsaturated Fatty Acid Intake to Peripheral Neuropathy Among Adults With Diabetes in the National Health and Nutrition Examination Survey (NHANES) 1999 2004
Diabetes Care, January 1, 2008; 31(1): 93 - 95.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.