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American Journal of Epidemiology Vol. 98, No. 5: 395-401
Copyright © 1973 by The Johns Hopkins University School of Hygiene and Public Health

other

RUBELLA DURING PREGNANCY AS A CAUSE OF CONGENITAL HEARING LOSS1

PAIVI OJALA2, TIMO VESIKARI 3 and OLAVI ELO4

2Department of Virology, University of Helsinki Haartmaninkatu 3, 00290 Helsinki 29, Finland
4Department of Epidemiology and Hygiene, National Board of Health Finland

A survey for rubella antibody was made on sera from 128 infants aged 6 months to 5 years with moderate or severe congenital hearing loss. Using the rubella hemagglutination-inhibition test, 57 (45%) were found seropositive. A history of rubella during pregnancy was given by 67% of mothers whose children had rubella antibodies. Postnatal rubella infection appeared to be rate in the infants. The majority of children with rubella antibody were born 6–8 months after an epidemic peak of rubella. Two epidemic years within the study period may have led to some bias for rubella as an etiologic factor in congenital hearing loss.

deafness; congenital; hearing disorders; rubella

1This study was carried out at the Department of Virology, University of Helsinki, Finland; and was supported by a research contract from National Board of Health, Finland.

3Current address; Rubella Project, Department of Pediatrics, New York University Medical Center, 550 First Ave., New York, N.Y. 10016.


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