American Journal of Epidemiology Advance Access originally published online on January 6, 2009
American Journal of Epidemiology 2009 169(5):562-571; doi:10.1093/aje/kwn370
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ORIGINAL CONTRIBUTIONS |
Cost-Effectiveness of Acupuncture in Women and Men With Allergic Rhinitis: A Randomized Controlled Study in Usual Care
Correspondence to Prof. Dr. Claudia M. Witt, Institute for Social Medicine, Epidemiology, and Health Economics, Charité University Medical Center, 10098 Berlin, Germany (e-mail: claudia.witt{at}charite.de).
Received for publication June 20, 2008. Accepted for publication October 22, 2008.
To assess quality of life and cost-effectiveness of additional acupuncture treatment for allergic rhinitis, patients were randomly allocated to 2 groups; both received usual care, but one group received an additional 10 acupuncture sessions. Quality of life (according to the SF-36 Health Survey), and direct and indirect costs, were assessed at baseline and after 3 months, and the incremental cost-effectiveness ratio of acupuncture treatment was calculated. This German study (December 2000–June 2004) involved 981 patients (64% women, mean age 40.9 years (standard deviation, 11.2); 36% men, mean age 43.2 years (standard deviation, 13.0)). At 3 months, quality of life was higher in the acupuncture group than in the control group (mean Physical Component Score 51.99 (standard error (SE), 0.33) vs. 48.25 (SE, 0.33), P < 0.001; mean Mental Component Score 48.55 (SE, 0.42) vs. 45.35 (SE, 0.42), respectively, P < 0.001). Overall costs in the acupuncture group were significantly higher than those in the control group (Euro (
;
1 = US $1.27)763, 95% confidence interval: 683, 844 vs.
332, 95% confidence interval: 252, 412; mean difference
432, 95% confidence interval: 318, 545). The incremental cost-effectiveness ratio was
17,377 per quality-adjusted life year (women,
10,155; men,
44,871) and was robust in sensitivity analyses. Acupuncture, supplementary to routine care, was beneficial and, according to international benchmarks, cost-effective. However, because of the study design, it remains unclear whether the effects are acupuncture specific.
acupuncture; cost-benefit analysis; economics; quality of life; rhinitis, allergic, perennial; rhinitis, allergic, seasonal
Abbreviations: CI, confidence interval; ICER, incremental cost-effectiveness ratio; QALY, quality-adjusted life year; SF-36, Self-Rated Health Survey