American Journal of Epidemiology Advance Access originally published online on February 17, 2008
American Journal of Epidemiology 2008 167(6):753-754; doi:10.1093/aje/kwn009
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American Journal of Epidemiology © The Author 2008. Published by the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org.
LETTERS TO THE EDITOR |
THE AUTHORS REPLY
1 Department of Environmental Health, Harvard School of Public Health, Boston, MA 02115
2 Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115
3 Department of Nutrition, Harvard School of Public Health, Boston, MA 02115
4 Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709
5 Department of Neurology, Massachusetts General Hospital, Boston, MA 02114
(e-mail: mweissko@hsph.harvard.edu)
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We appreciate Dr. Wise's thoughtful comments (1). We agree that it would have been premature—based on the epidemiologic data we presented (2)—to recommend that plasma urate levels be increased in order to reduce the risk and delay