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American Journal of Epidemiology Advance Access originally published online on June 2, 2006
American Journal of Epidemiology 2006 164(2):122-125; doi:10.1093/aje/kwj194
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American Journal of Epidemiology Copyright © 2006 by the Johns Hopkins Bloomberg School of Public Health All rights reserved; printed in U.S.A.

Invited Commentary

Invited Commentary: Beyond Frequencies and Coefficients—Toward Meaningful Descriptions for Life Course Epidemiology

Constance Wang

From the Division of Epidemiology and the Division of Community Health and Human Development, School of Public Health, University of California, Berkeley, CA

Correspondence to Dr. Constance Wang, Division of Epidemiology and Division of Community Health and Human Development, School of Public Health, University of California, 140 Warren Hall, MC 7360, Berkeley, CA 94720-7360 (e-mail: constancew@berkeley.edu).

Received for publication February 17, 2006. Accepted for publication February 28, 2006.

The first 150 words of the full text of this article appear below.


   INTRODUCTION
 
The expected doubling of the elderly population in the United States by year 2030 poses a major challenge to public health and medical care systems because of limited and progressive diminution of resources for public health and medical care for the elderly (1Go). This challenge highlights the urgent need for effective programs and policies aimed at the prevention of diseases and maintenance of health over the life span of individuals. Such programs must rely on solid, translatable evidence from population-based etiologic studies. However, both etiologic studies of healthy aging and the translation of study findings into programs and policies are exceedingly complex. For example, to identify accurately and precisely the predictors of the onset and the progression of diseases and functional decline, we must contend with not only 1) multiple arrays of time-varying risk and protective factors and 2) multiple morbidities and functional outcomes over time but also 3) . . . [Full Text of this Article]


   HOW SHOULD WE EXAMINE INTERRELATED MEASURES OVER THE LIFE SPAN?
 

   WHAT IS THE CONTRIBUTION OF THE SOCIOECONOMIC CONTEXT?
 

   SHOULD WE MOVE AWAY FROM THE ONE RISK FACTOR–ONE OUTCOME APPROACH?
 

   HOW DO WE INVESTIGATE DEVELOPMENTAL/AGING PROCESSES AS CUMULATIVE PROCESSES?
 

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