Am J Epidemiol 2004; 159:702-706.
Copyright © 2004 by the Johns
Hopkins Bloomberg School of Public Health
ORIGINAL CONTRIBUTIONS |
A Modified Poisson Regression Approach to Prospective Studies with Binary Data
1 Robarts Clinical Trials, Robarts Research Institute, London, Ontario, Canada.
2 Department of Epidemiology and Biostatistics, University of Western Ontario, London, Ontario, Canada.
Relative risk is usually the parameter of interest in epidemiologic and medical studies. In this paper, the author proposes a modified Poisson regression approach (i.e., Poisson regression with a robust error variance) to estimate this effect measure directly. A simple 2-by-2 table is used to justify the validity of this approach. Results from a limited simulation study indicate that this approach is very reliable even with total sample sizes as small as 100. The method is illustrated with two data sets.
clinical trials; cohort studies; logistic regression; Mantel-Haenszel; odds ratio; relative risk
Abbreviations: Abbreviations: CI, confidence interval; RR, relative risk.
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 T. I Ibiebele, J. C van der Pols, M. C. Hughes, G. C Marks, G. M Williams, and A. C Green Dietary pattern in association with squamous cell carcinoma of the skin: a prospective study Am. J. Clinical Nutrition, May 1, 2007; 85(5): 1401 - 1408. [Abstract] [Full Text] [PDF]
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F. C. Lampe, C. J. Smith, S. Madge, S. Kinloch-de Loes, M. Tyrer, C. A. Sabin, C. Chaloner, M. Youle, M. A. Johnson, and A. N. Phillips Success of Clinical Care for Human Immunodeficiency Virus Infection According to Demographic Group Among Sexually Infected Patients in a Routine Clinic Population, 1999 to 2004 Arch Intern Med, April 9, 2007; 167(7): 692 - 700. [Abstract] [Full Text] [PDF]
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C. Ferreccio, A. Rollan, P. R. Harris, C. Serrano, A. Gederlini, P. Margozzini, C. Gonzalez, X. Aguilera, A. Venegas, and A. Jara Gastric Cancer is Related to Early Helicobacter pylori Infection in a High-Prevalence Country Cancer Epidemiol. Biomarkers Prev., April 1, 2007; 16(4): 662 - 667. [Abstract] [Full Text] [PDF]
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J. Ahnquist, P. Fredlund, and S. P Wamala Is cumulative exposure to economic hardships more hazardous to women's health than men's? A 16-year follow-up study of the Swedish Survey of Living Conditions J Epidemiol Community Health, April 1, 2007; 61(4): 331 - 336. [Abstract] [Full Text] [PDF]
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 C. L. Booth, A. M. Garcia-Diaz, M. S. Youle, M. A. Johnson, A. Phillips, and A. M. Geretti Prevalence and predictors of antiretroviral drug resistance in newly diagnosed HIV-1 infection J. Antimicrob. Chemother., March 1, 2007; 59(3): 517 - 524. [Abstract] [Full Text] [PDF]
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D. A. Thompson, P. Lozano, and D. A. Christakis Parent Use of Touchscreen Computer Kiosks for Child Health Promotion in Community Settings Pediatrics, March 1, 2007; 119(3): 427 - 434. [Abstract] [Full Text] [PDF]
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N. Nagot, A. Ouedraogo, V. Foulongne, I. Konate, H. A. Weiss, L. Vergne, M.-C. Defer, D. Djagbare, A. Sanon, J.-B. Andonaba, et al. Reduction of HIV-1 RNA Levels with Therapy to Suppress Herpes Simplex Virus N. Engl. J. Med., February 22, 2007; 356(8): 790 - 799. [Abstract] [Full Text] [PDF]
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 G. Y. Zou One relative risk versus two odds ratios: implications for meta-analyses involving paired and unpaired binary data Clinical Trials, February 1, 2007; 4(1): 25 - 31. [Abstract] [PDF]
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 C. O. Weiss, L. P. Fried, and K. Bandeen-Roche Exploring the Hierarchy of Mobility Performance in High-Functioning Older Women J. Gerontol. A Biol. Sci. Med. Sci., February 1, 2007; 62(2): 167 - 173. [Abstract] [Full Text] [PDF]
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