Am J Epidemiol 2002; 156:297-299.
Copyright © 2002 by the
Johns Hopkins Bloomberg School of Public Health
HUMAN GENOME EPIDEMIOLOGY |
Commentary: Epidemiology and the Continuum from Genetic Research to Genetic Testing
From the Office of Genomics and Disease Prevention, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA.
Received for publication September 5, 2001; accepted for publication June 13, 2002.
Abbreviations: Abbreviation: HuGE, Human Genome Epidemiology.
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INTRODUCTION |
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In January 2001, the Centers for Disease Control and Prevention and the National Institutes of Health convened an expert panel to develop recommendations for evaluating and synthesizing data from epidemiologic studies of the human genome. Experts in medicine, genetics, epidemiology, statistics, laboratory sciences, prevention effectiveness, and the social sciences discussed examples drawn from cancer, cardiovascular disease, human immunodeficiency virus infection, and other areas. Participants discussed issues for evaluating and synthesizing data from epidemiologic and genetic test studies (table 1) relevant to three areas: 1) prevalence of gene variants and gene-disease associations, 2) gene-environment and gene-gene interactions, and 3) evaluation of genetic tests. The workshop recommendations in areas 1 and 3 are included in this issue of the Journal (1, 2). The recommendations of area 2 (gene-environment interaction)
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NEED FOR STANDARDS FOR REPORTING AND SYNTHESIS OF EPIDEMIOLOGY AND GENETIC TEST DATA |
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