American Journal of Epidemiology Vol. 154, No. 7 : 601-609
Copyright © 2001 by The Johns Hopkins University School of Hygiene and Public Health
ORIGINAL CONTRIBUTIONS |
Effects of Electric and Magnetic Fields from High-power Lines on Female Urinary Excretion of 6-Sulfatoxymelatonin
1 Unité de recherche en santé publique, Pavillon CHUL, Centre hospitalier universitaire de Québec, Québec, Canada.
2 Institut national de santé publique du Québec and Université Laval, Québec, Canada.
3 Chronobiology Laboratory, Hôpital du Sacré-C
ur and Université de Montréal, Québec, Canada.
4 Service de Biochimie, Faculté de médecine Pitié-Salpétrière, Paris, France.
5 Groupe de recherche en épidémiologie, Hôpital du Saint-Sacrement, Centre hospitalier affilié universitaire de Québec, Québec, Canada.
6 Institut de recherche d'Hydro-Québec, Varennes, Québec, Canada.
7 Service de Biochimie, Hôpital de l'Hôtel-Dieu de Québec, Québec, Canada.
In 1998, the authors studied the effect of residential exposure to electric and magnetic fields from high-power lines on female urinary excretion of 6-sulfatoxymelatonin (6-OHMS) in the Quebec city, Canada, metropolitan area. A sample of 221 women living near a 735-kV line was compared with 195 women the same age living away from any power lines. Participants provided morning urine samples on 2 consecutive days and wore a magnetic dosimeter for 36 consecutive hours to measure personal magnetic exposure. The indoor electric field was assessed by spot measurements. After adjustment for other factors associated with low melatonin secretion, such as medication use or light exposure, nighttime concentration of 6-OHMS was similar in the two groups. When either 24-hour or sleep-time exposure to magnetic field or electric field measurements was used, no exposure-effect relation was evident. However, the trend of decreasing 6-OHMS concentration with age was more pronounced for women living near the lines, as was a lower 6-OHMS concentration in women with high body mass index. Chronic residential exposure to magnetic fields from high-power lines may accentuate the decrease in melatonin secretion observed in some vulnerable subgroups of the population.
age factors; body mass index; electromagnetic fields; melatonin; urinalysis
Abbreviations: BMI, body mass index; EMF, electric and magnetic fields; 6-OHMS, 6-sulfatoxymelatonin
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