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American Journal of Epidemiology Vol. 154, No. 3 : 230-235
Copyright © 2001 by The Johns Hopkins University School of Hygiene and Public Health


ORIGINAL CONTRIBUTIONS

Effects of an Angry Temperament on Coronary Heart Disease Risk

The Atherosclerosis Risk in Communities Study

Janice E. Williams1, F. Javier Nieto2, Catherine P. Sanford3 and Herman A. Tyroler4

1 Cardiovascular Health Branch, Centers for Disease Control and Prevention, Atlanta, GA.
2 Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD.
3 Injury and Violence Prevention Unit, North Carolina Department of Health and Human Services, Raleigh, NC.
4 Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC.

The objective of the study was to determine which component of an anger-prone personality more strongly predicts coronary heart disease (CHD) risk. Proneness to anger, as assessed by the Spielberger Trait Anger Scale, is composed of two distinct subcomponents—anger-temperament and anger-reaction. Participants were 12,990 middle-aged Black men and women and White men and women from the Atherosclerosis Risk in Communities Study who were followed for the occurrence of acute myocardial infarction (MI)/fatal CHD, silent MI, or cardiac revascularization procedures (average = 53 months; maximum = 72 months) through December 31, 1995. Among normotensive persons, a strong, angry temperament (tendency toward quick, minimally provoked, or unprovoked anger) was associated with combined CHD (acute MI/fatal CHD, silent MI, or cardiac revascularization procedures) (multivariate-adjusted hazard ratio = 2.10, 95% confidence interval: 1.34, 3.29) and with ‘hard" events (acute MI/fatal CHD) (multivariate adjusted hazard ratio = 2.28, 95% confidence interval: 1.29, 4.02). CHD event-free survival among normotensives who had a strong, angry temperament was not significantly different from that of hypertensives at either level of anger. These data suggest that a strong, angry temperament rather than anger in reaction to criticism, frustration, or unfair treatment places normotensive, middle-aged persons at increased risk for cardiac events and may confer a CHD risk similar to that of hypertension.

coronary disease; prospective studies; stress; survival analysis

Abbreviations: ARIC, Atherosclerosis Risk in Communities; CHD, coronary heart disease; MI, myocardial infarction.


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