American Journal of Epidemiology, Vol 152, Issue 9 805-813, Copyright © 2000 by Oxford University Press
DA Murphy, S Durako, LR Muenz and CM Wilson
The validity of self-report of drug use has been found to vary widely.
Moreover, previous research has focused on samples of adults. In 1996-
1998, human immunodeficiency virus (HIV)-infected adolescents and high-
risk, noninfected adolescents (n = 182) were recruited at 16 locations in
13 US cities into the Reaching for Excellence in Adolescent Care and Health
(REACH) project, to the authors' knowledge, the first national study of
disease progression among HIV-positive adolescents who were infected
through sexual behavior or injection drug use. Self-report of marijuana use
was assessed through audio computer-assisted self- administered
interviewing (ACASI). Urines were tested for marijuana at a certified
laboratory by using the enzyme-multiplied immunoassay technique.
Conditional kappas for 2-, 5-, and 7-day self-reports were 0.57, 0.71, and
0.69, respectively. Maximum sensitivity was obtained from a combination of
ACASI and urine drug testing. Contrary to previous studies, the data
suggest that if a single evaluative instrument is to be used for
prevalence, ACASI is more sensitive than urine drug testing for marijuana
overall, but particularly for HIV- infected adolescents.
Marijuana use among HIV-positive and high-risk adolescents: a comparison of self-report through audio computer-assisted self- administered interviewing and urinalysis [In Process Citation]
Department of Psychiatry, University of California, Los Angeles 90025- 7510, USA. dmurphy@mednet.ucla.edu
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