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American Journal of Epidemiology Vol. 152, No. 2 : 193
Copyright © 2000 by The Johns Hopkins University School of Hygiene and Public Health

LETTERS TO THE EDITOR

RE: "INTERACTION BETWEEN TOBACCO AND ALCOHOL CONSUMPTION AND THE RISK OF CANCERS OF THE UPPER AERO-DIGESTIVE TRACT IN BRAZIL"

William J. Waddell and Paul S. Levy

Department of Pharmacology and Toxicology School of Medicine University of Louisville Louisville, KY 40292
Division of Epidemiology and Biostatistics School of Public Health University of Illinois at Chicago Chicago, IL 60612–7260


   INTRODUCTION
 
Schlecht et al. (1Go) continue the same long-standing confusion in interpretation of the data on the relation of smoking and drinking as independent risk factors for cancer of the upper aero-digestive tract (UADT). They studied 784 patients with cancer of the oral cavity, pharynx, and larynx for smoking and drinking habits and other characteristics. Since virtually all of these cases both smoked and drank, the authors used statistical methods in an attempt to determine the effect of each of these two habits. This is the same method that has been used in many other, similar studies, leading some to conclude that drinking is an independent risk factor. However, this is very problematic since other biologic data show that, although potent carcinogens exist in tobacco smoke, alcohol . . . [Full Text of this Article]


   REFERENCES
 
Nicolas F. Schlecht and Eduardo L. Franco

Departments of Epidemiology and Oncology McGill University Montreal, Quebec, Canada H2W 1S6


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Home page
 Am J EpidemiolHome page
W. J. Waddell, P. S. Levy, N. F. Schlecht, and E. L. Franco
RE: "INTERACTION BETWEEN TOBACCO AND ALCOHOL CONSUMPTION AND THE RISK OF CANCERS OF THE UPPER AERO-DIGESTIVE TRACT IN BRAZIL"
Am. J. Epidemiol., July 15, 2000; 152(2): 193 - 193.
[Full Text] [PDF]