American Journal of Epidemiology Vol. 136, No. 4: 422-427
Copyright © 1992 by The Johns Hopkins University School of Hygiene and Public Health
research-article |
Reduced Cancer Morbidity and Mortality in a Prospective Cohort of Women with Distal Forearm Fractures
1Department of Oncology, University Hospital Lund S-221 85, Sweden
2Department of Orthopedics, University Hospital Lund 5-221 85, Sweden
Reprint requests to Dr. Håkan Olsson, Department of Oncology, University Hospital, Lurid 5-221 85, Sweden
At the Department of Orthopedics of University Hospital, Lund, Sweden, cancer incidence and overall and cause-specific mortality were studied in a prospective cohort of 677 women who had experienced a fracture of the distal forearm in 1974 or 1975. The women were followed through population-based population, cancer, and death registries in southern Sweden. There was a significant reduction In overall cancer incidence (66 cases observed vs. 90.21 expected), breast cancer incidence (11 cases observed vs. 20.31 cases expected), and incidence of tumors of the female genital tract (5 cases observed vs. 11.84 expected). Overall mortality was also reduced (146 cases observed vs. 191.69 cases expected), and rates of death from circulatory disease (79 cases observed vs. 111.49 expected) and malignant tumors (30 cases observed vs. 40.41 expected) were both tower than expected.
breast neoplasms; cohert studies; estrogens; fractures; morbidity; mortality; neoplasms; osteoparosis
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