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American Journal of Epidemiology Vol. 136, No. 10: 1241-1247
Copyright © 1992 by The Johns Hopkins University School of Hygiene and Public Health

research-article

Calcium Intake and Blood Pressure in Elderly Women

Joel A. Simon1,2,, Warren S. Browner1,2, Jo Law Tao2 and Stephen B. Hulley2

1General Internal Medicine Section, Department of Medicine, Veterans Affairs Medical Center San Francisco, CA.
2Division of Clinical EptdemioJogy, Department of Epidemiology and Biostatistics, University of California San Francisco, CA

Reprint requests to Dr. Joel A. Simon, General Internal Medcine Section (111A1), Veterans Affajrs Medical Center, 4150 Clement Street, San Francisco, CA 94121.

The authors studied the relative importance of calcium intake as a correlate of Wood pressure in a cross-sectional analysis of 6, 517 nonblack women aged >65 years from Portland, Oregon; Minneapolis, Minnesota; Baltimore, Maryland; and the Monongahela Valley near Pittsburgh, Pennsylvania, who enrolled in the Study of Osteoporotic Fractures in 1986. Dietary calcium intake was measured by using a modified food frequency questionnaire. There were weak associations between total calcium intake and Wood pressure, such that each 1, 000 mg/day increase in calcium intake was associated with a 1.5 mmHg decrease in systWic blood pressure (95% confidence interval –2.2 to –0.8, p < 0.0001) and a 0.5 mmHg decrease in diastWic pressure (95% confidence interval –0.8 to –0.20, p < 0.004). After adjustment for confounding variables, total calcium intake continued to have a weak inverse association only with diastolic Wood pressure. The multivariate models revealed several stronger independent risk factors for blood pressure, including age, body mass index, alcohol consumption, and level of education (all p < 0.01). The small size of the inverse association between calcium intake and blood pressure limits its Wotogical importance in this population of elderly women. Am J Epidemiol 1992; 136: 1241–7

blood pressure; calcium; women


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