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American Journal of Epidemiology Vol. 134, No. 9: 998-1002
Copyright © 1991 by The Johns Hopkins University School of Hygiene and Public Health

research-article

Validation of a Questionnaire on Medical Drug Use during Pregnancy

P. C. M. de Jong1,, A. A. Huijsmans1, H. E. Nienhuis1, W. S. Nijdam2, G. A. Zielhuis1 and T. K. A. B. Eskes2

1Department of Epidemiology, University of Nijmegen Nijmegen, the Netherlands
2Department of Obstetrics and Gynecology, University Hospital Nijmegen, the Netherlands

Reprint requests to P C. M. de Jong, Department of Epidemiology, P. 0. Box 9101, 6500 HB Nijmegen, the Netherlands

The validity of a questionnaire on medical drug use during pregnancy was tested against information collected 7 years previously (in 1983–1984) at the University Hospital of Nijmegen, the Netherlands. The study population consisted of women with high-risk pregnancies. The sensitivity for drug categories varied between 0% and 80%. The sensitivity was highest for drugs used during labor (77%) and was extremely low (0%) for some drug categories. Personal characteristics thought to influence the sensitivity, such as parity of the mother and method of data collection (postal questionnaire or personal interview), showed no statistically significant effect. The newly developed questionnaire needs further improvement.

data collection; drug utilization; pregnancy; questionnaires; reproducibility of result


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