American Journal of Epidemiology Vol. 132, No. 6: 1102-1110
Copyright © 1990 by The Johns Hopkins University School of Hygiene and Public Health
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RISK FACTORS FOR CARPAL TUNNEL SYNDROME
1Department of Neurology, Maastricht University Hospital, University of Limburg Maastricht, The Netherlands
2Department of Medical Informatics and Statistics, University of Limburg Maastricht, The Netherlands
3Department of Epidemiology and Health Care Research, University of Limburg Maastncht, The Netherlands
4Department of Clinical Neurophysiology, Maastricht Umversity Hospital, University of Limburg Maastricht, the Netherlands
Reprint requests to Dr. M. C. T. F. M de Krom, Department of Neurology, Manstricht University Hospital, P. 0 Box 1918, 6201 BX Maastricht, The Netherlands
Between September 1983 and July 1985, a case-control study was performed of carpal tunnel syndrome risk factors in the general population of Maastricht, The Netherlands, and some surrounding villages. Twenty-eight of the 501 participants were found to suffer from carpal tunnel syndrome. These 28 were added to a series 01128 consecutive carpal tunnel syndrome patients from the same area. The 156(131 women and 25 men) subjects in whom carpal tunnel syndrome had been diagnosed on the basis of clinical history and neurophyslologic testing were compared with the remaining 473(310 women and 163 men) subjects. After adjustment for age and sex, the following carpal tunnel syndrome risk factors could be identified: activities with a flexed wrist or with an extended wrist (exposure-related increased risk), hysterectomy without oophorectomy, last men strual period in menopausal women 6–12 months ago, height, weight, Quetetet index, slimming courses, and in men, varicosis. Associations between carpal tunnel syndrome and the use of oral contraceptives, age at menopause, diabetes, thyroid dysfunction, rheumatism, typing, and pinch grasp could not be demonstrated.
carpal tunnel syndrome; case-control studies; risk factors
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