American Journal of Epidemiology Vol. 129, No. 4: 687-702
Copyright © 1989 by The Johns Hopkins University School of Hygiene and Public Health
research-article |
THE ATHEROSCLEROSIS RISK IN COMMUNIT (ARIC) STUI)Y: DESIGN AND OBJECTWES
Atherosclerosis Risk in Communities (ARIC) is a new prospective study to investigate the etiology of atherosclerosis and its clinical sequelae and variation in cardiovascular risk factors, medical care, and disease by race, sex, place, and time. in each of four US communities—Forsyth County, North Carolina, Jackson, Mississippi, suburbs of Minneapolis, Minnesota, and Washington County, Maryland—4, 000 adults aged 45–64 years will be examined twice, three years apart. ARIC has coordinating, ultrasound, pulmonary, and electrocardiographic centers and three central laboratories. Three cohorts represent the ethnic mix of their communities; the Jackson cohort, its black population. Examinations include ultrasound scanning of carotid and popliteal arteries; lipids, lipoprotelns, and apolipoproteins assayed in the Lipid Laboratory; and coagulation, inhibition, and platelet and fibrinolytic actmty assayed in the Hemostasis Laboratory. Surveil lance for coronary heart disease will involve review of hospitalizations and deaths among community residents aged 35–74 years. ARIC aims to study atheroscle rosis by direct observation of the disease and by use of modem biochemistry.
arteriosclerosis; cardiovascular diseases; coronary disease; hemostasis; Ilpoproteins
1The ARIC Steering Committee: Department of Epidemiology, The Johns Hopkins University, Balti more, MD—Moyses Szklo, Chairperson; Bowman Gray School of Medicine, Winston-Salem, NC—Ralph Barnes; Division of Epidemiology, University of Minnesota, Minneapolis, MN—Aaron Folsom; De partment of Epidemiology, University of North Car olina, Chapel Hill, NC—Gerardo Heiss; Department of Medicine, University of Mississippi Medical Center, Jackson, MS—Richard Hutchinson; Department of Internal Medicine, Baylor College of Medicine, Houston, TX—Wolfgang Patach; Epidemiology and Biom etry Program, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD—A. Richey Sharrett Department of Biostatistics, Uni versity of North Carolina, Chapel Hill, NC—O. Dale Williams; Division of Hematology-Oncology, University of Texas Medical School at Houston, Houston, TX— Kenneth Wu
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H.-C. Yeh, N. M. Punjabi, N.-Y. Wang, J. S. Pankow, B. B. Duncan, C. E. Cox, E. Selvin, and F. L. Brancati Cross-Sectional and Prospective Study of Lung Function in Adults With Type 2 Diabetes: The Atherosclerosis Risk in Communities (ARIC) Study Diabetes Care, April 1, 2008; 31(4): 741 - 746. [Abstract] [Full Text] [PDF]
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T. Rundek, H. Arif, B. Boden-Albala, M. S. Elkind, M. C. Paik, and R. L. Sacco Carotid plaque, a subclinical precursor of vascular events: The Northern Manhattan Study Neurology, April 1, 2008; 70(14): 1200 - 1207. [Abstract] [Full Text] [PDF]
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G. Liew, J. J. Wang, B. B. Duncan, R. Klein, A. R. Sharrett, F. Brancati, H.-C. Yeh, P. Mitchell, T. Y. Wong, and for the Atherosclerosis Risk in Communities Study Low Birthweight Is Associated With Narrower Arterioles in Adults Hypertension, April 1, 2008; 51(4): 933 - 938. [Abstract] [Full Text] [PDF]
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E. Shahar, G. Heiss, W. D. Rosamond, and M. Szklo Baldness and Myocardial Infarction in Men: The Atherosclerosis Risk in Communities Study Am. J. Epidemiol., March 15, 2008; 167(6): 676 - 683. [Abstract] [Full Text] [PDF]
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H. Kan, J. Stevens, G. Heiss, K. M. Rose, and S. J. London Dietary Fiber, Lung Function, and Chronic Obstructive Pulmonary Disease in the Atherosclerosis Risk in Communities Study Am. J. Epidemiol., March 1, 2008; 167(5): 570 - 578. [Abstract] [Full Text] [PDF]
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H. Bang, M. Mazumdar, L. M. Kern, D. A. Shoham, P. A. August, and A. V. Kshirsagar Validation and Comparison of a Novel Screening Guideline for Kidney Disease: KEEPing SCORED Arch Intern Med, February 25, 2008; 168(4): 432 - 435. [Full Text] [PDF]
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P. L. Lutsey, L. M. Steffen, and J. Stevens Dietary Intake and the Development of the Metabolic Syndrome: The Atherosclerosis Risk in Communities Study Circulation, February 12, 2008; 117(6): 754 - 761. [Abstract] [Full Text] [PDF]
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 A. Z. Fan, M. Russell, S. Stranges, J. Dorn, and M. Trevisan Association of Lifetime Alcohol Drinking Trajectories with Cardiometabolic Risk J. Clin. Endocrinol. Metab., January 1, 2008; 93(1): 154 - 161. [Abstract] [Full Text] [PDF]
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 H. Kan, J. Stevens, G. Heiss, R. Klein, K. M Rose, and S. J London Dietary fiber intake and retinal vascular caliber in the Atherosclerosis Risk in Communities Study Am. J. Clinical Nutrition, December 1, 2007; 86(6): 1626 - 1632. [Abstract] [Full Text] [PDF]
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 B. M. Psaty, D. Arnett, and G. Burke A New Era of Cardiovascular Disease Epidemiology JAMA, November 7, 2007; 298(17): 2060 - 2062. [Full Text] [PDF]
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 L. M. Reich, G. Heiss, L. L. Boland, A. T. Hirsch, K. Wu, and A. R. Folsom Ankle brachial index and hemostatic markers in the Atherosclerosis Risk in Communities (ARIC) study cohort Vascular Medicine, November 1, 2007; 12(4): 267 - 273. [Abstract] [PDF]
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M. J. Domanski Primary Prevention of Coronary Artery Disease N. Engl. J. Med., October 11, 2007; 357(15): 1543 - 1545. [Full Text] [PDF]
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H. Kan, G. Heiss, K. M Rose, E. Whitsel, F. Lurmann, and S. J London Traffic exposure and lung function in adults: the Atherosclerosis Risk in Communities study Thorax, October 1, 2007; 62(10): 873 - 879. [Abstract] [Full Text] [PDF]
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E. R. Fox, N. Alnabhan, A. D. Penman, K. R. Butler, H. A. Taylor Jr, T. N. Skelton, and T. H. Mosley Jr Echocardiographic Left Ventricular Mass Index Predicts Incident Stroke in African Americans: Atherosclerosis Risk in Communities (ARIC) Study Stroke, October 1, 2007; 38(10): 2686 - 2691. [Abstract] [Full Text] [PDF]
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J. D. Sturgeon, A. R. Folsom, W.T. Longstreth Jr, E. Shahar, W. D. Rosamond, and M. Cushman Risk Factors for Intracerebral Hemorrhage in a Pooled Prospective Study Stroke, October 1, 2007; 38(10): 2718 - 2725. [Abstract] [Full Text] [PDF]
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 M. S. Player, D. E. King, A. G. Mainous III, and M. E. Geesey Psychosocial Factors and Progression From Prehypertension to Hypertension or Coronary Heart Disease Ann. Fam. Med, September 1, 2007; 5(5): 403 - 411. [Abstract] [Full Text] [PDF]
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N. Cheung, A. Shankar, R. Klein, A. R. Folsom, D. J. Couper, T. Y. Wong, and for the Atherosclerosis Risk in Communities (ARIC) Age-Related Macular Degeneration and Cancer Mortality in the Atherosclerosis Risk in Communities Study Arch Ophthalmol, September 1, 2007; 125(9): 1241 - 1247. [Abstract] [Full Text] [PDF]
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