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American Journal of Epidemiology Vol. 118, No. 3: 360-364
Copyright © 1983 by The Johns Hopkins University School of Hygiene and Public Health

other

ACUTE SPORADIC NON-A, NON-B HEPATITIS IN INDIA

MOHAMMAD SULTAN KHUROO, WILLIAM DUERMEYER1, SHOWKAT ALI ZARGAR, MOHAMMAD ASHRAF AHANGER and MANZOOR AHMAD SHAH

1Microbiological Research and Development Laboratories, Organon International BV Oss, The Netherlands

Khuroo, M. S. (Institute of Medical Sciences, Srinagar, Kashmir, India), W. Duermeyer, S. A. Zargar, M. A. Ahanger and M. A. Shah. Acute sporadic non-A, non-B hepatitis in India. Am J Epidemiol 1983; 118: 360–4.

A total of 293 sporadic cases of acute viral hepatitis were identified in Kashmir, India, from April 1979 to December 1981; 44 (15%) were found serologically to be hepatitis A, 94 (32%) hepatitis B, and 155 (53%) non-A, non-B type. The non-A, non-B hepatitis observed was a disease of young adults (29.8 ±15 years) with slight male predominance (1.4: 1). Six of the 155 non-A, non-B cases had history of prior parenteral exposure, while 51 (33%) had a recent contact with another case of jaundice, suggesting that this form of hepatitis was spread by person-to-person contact. Fulminant hepatic failure occurred in 19 cases, and six (31.5%) of the 19 cases occurred in pregnant women. None of 90 non-A, non-B cases followed up six months later had developed chronic hepatitis. The acute sporadic non-A, non-B hepatitis described in Kashmir resembles epidemic non-A, non-B hepatitis epidemiologically and seems to be distinct from the non-A, non-B hepatitis described in the West.

hepatitis A; hepatitis B; hepatitis; viral; non-A; non-B


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