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American Journal of Epidemiology Vol. 113, No. 1: 22-29
Copyright © 1981 by The Johns Hopkins University School of Hygiene and Public Health


other

EPSTEIN-BARR VIRUS INFECTIONS IN A NURSERY

R. SHIHMAN CHANG1,, LEON ROSEN2 and ALBERT Z. KAPIKIAN3

1Department of Medical Microbiology, University of California, School of Medicine Davis, CA 95616
2Pacific Research Unit, Research Corporation of the University of Hawaii Honolulu
3Laboratory of Infectious Diseases, National Institutes of Health Bethesda, MD

1reprint requests to Dr.Chang

Chang, R. S. (Dept. of Medical Microbiology, U. of California, School of Medicine, Davis, CA 95616), L. Rosen and A. Z. Kapikian. Epstein-Barr virus Infections In a nursery. Am J Epidemiol 1981;113:22–9.

Tests for Epstein-Barr virus (EBV) capsid antibody were carried out on 115 children, aged 4–32 months, on admission to and discharge from the Junior Village nursery, Washington, D.C. Forty-three children positive on admission remained positive at discharge, 44/72 negative on admission remained negative at discharge, and 28/72 negative on admission converted to positive at discharge. Age, sex and season did not appear to influence the rate of EBV seroconversion among the nursery children. The only identifiable factor that significantly Increased the rate of EBV seroconversion was the duration of nursery residency. The rates were 1/9 (11%), 1/29 (3%), and 11/16 (69%) among children residing for 1.5–2.4, 2.5–4.4 and 4.5–7.4 months, respectively. Children residing in the nursery for 1.5–4.4 months and children residing at home had similar EBV-seroconversion rates. For children residing in the nursery for 4.5–7.4 months, however, the observed EBV-seroconversion rate was much higher than the rate estimated for children living at home.

Epstein-Barr virus; nursery


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Home page
Arch Pediatr Adolesc MedHome page
C. T. Le, R. S. Chang, and M. H. Lipson
Epstein-Barr Virus Infections During Pregnancy: A Prospective Study and Review of the Literature
Arch Pediatr Adolesc Med, May 1, 1983; 137(5): 466 - 468.
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