Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (75)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by GLASS, R. I.
Right arrow Articles by KAHN, E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by GLASS, R. I.
Right arrow Articles by KAHN, E.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

American Journal of Epidemiology Vol. 109, No. 3: 346-351
Copyright © 1979 by The Johns Hopkins University School of Hygiene and Public Health

other

SPERM COUNT DEPRESSION IN PESTICIDE APPLICATORS EXPOSED TO DIBROMOCHLOROPROPANE

R. I. GLASS1,1, R N. LYNESS2, D. C. MENGLE2, K. E. POWELL1 and E. KAHN2

1 Chronic Diseases Division, Bureau of Epidemiology, Center for Disease Control Atlanta, GA 30333
2 Community Studies on Pesticides, California Department of Health Berkeley, CA 94704
3 Epidemiological Studies Laboratory, California Department of Health Berkeley, CA 94704

1Reprint requests to Dr. Roger Glass at this address

Male pesticide applicators who worked with the nematocide dibromochloropropane (DBCP) were examined to determine the possible testicular toxicity from this exposure. Infertility and azoospermia which were first noted among factory workers exposed to DBCP were not observed among the applicators. Sperm count depression, however, was associated with the duration of exposure in the current year but not with exposure in past years. The extent of exposure to DBCP in the current year was also associated with an elevation of serum follicle stimulating hormone (FSH) but not of lutelnizing hormone (LH). Sperm count depression was limited to applicators involved in irrigation setup work and In the calibration of equipment. These results suggest that the testicular toxicity of DBCP for men may occur In a shorter period than was previously reported, that the effect may be reversible in men with mild sperm count depression, and that public health measures might be directed at controlling specific application techniques.

antinematodal agents; FSH; hydrocarbons; halogenated; LH; occupational diseases; oligospermia; propane; sterility


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Toxicol SciHome page
M. L. Meistrich, G. Wilson, K. L. Porter, I. Huhtaniemi, G. Shetty, and G. A. Shuttlesworth
Restoration of Spermatogenesis in Dibromochloropropane (DBCP)-Treated Rats by Hormone Suppression
Toxicol. Sci., December 1, 2003; 76(2): 418 - 426.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
J. W. Dallinga, E. J.C. Moonen, J. C.M. Dumoulin, J. L.H. Evers, J. P.M. Geraedts, and J. C.S. Kleinjans
Decreased human semen quality and organochlorine compounds in blood
Hum. Reprod., August 1, 2002; 17(8): 1973 - 1979.
[Abstract] [Full Text] [PDF]

Home page
 Hum Exp ToxicolHome page
K B. Rhouma, O Tebourbi, R Krichah, and M Sakly
Reproductive toxicity of DDT in adult male rats
Human and Experimental Toxicology, August 1, 2001; 20(8): 393 - 397.
[Abstract] [PDF]

Home page
 ScienceHome page
T Hudec, J Thean, D Kuehl, and R. Dougherty
Tris(dichloropropyl)phosphate, a mutagenic flame retardant: frequent cocurrence in human seminal plasma
Science, February 27, 1981; 211(4485): 951 - 952.
[Abstract] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.