American Journal of Epidemiology Vol. 107, No. 6: 479-487
Copyright © 1978 by The Johns Hopkins University School of Hygiene and Public Health
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CORONARY RISK AND ESTROGEN USE IN POSTMENOPAUSAL WOMEN1
2 Reprint requests to Dr. Pfeffer, Department of Neurology, University of California Irvine Medical Center, 101 City Drive South, Orange, CA 92668.
Of some 15,500 women resident In a retirement community during an 11-year Interval, 220 suffered a cardiologically ascertained first myocardial infarction. A case-control study demonstrated no association between estrogen use and myocardial infarction. The observed lack of association may be explained by an already high coronary risk in this age group, by the low daily estrogen dose, and by the short duration of estrogen use. The well-known association between hypertension and myocardial Infarction was confirmed.
aging; coronary disease; estrogen; hypertension; menopause; myocardial Infarct
1Departments of Neurology and Medicine, University of California, Irvine, California College of Medicine and the UCLA School of Public Health
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