American Journal of Epidemiology Advance Access originally published online on September 4, 2007
American Journal of Epidemiology 2007 166(9):1105; doi:10.1093/aje/kwm250
American Journal of Epidemiology © The Author 2007. Published by the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org.
RE: "PARENTAL INFERTILITY AND SEMEN QUALITY IN MALE OFFSPRING: A FOLLOW-UP STUDY"
Tina Kold Jensen1,2,
Niels Jørgensen1,
Camilla Asklund1 and
Niels E. Skakkebæk1
1 University Department of Growth and Reproduction, Rigshospitalet, 2100 Copenhagen Ø, Denmark
2 Department of Environmental Medicine, University of Southern Denmark, DK-5230 Odense M, Denmark
(e-mail: tkjensen{at}health.sdu.dk)
In their recent Journal article, "Parental Infertility and Semen Quality in Male Offspring: A Follow-up Study," Ramlau-Hansen et al. (1) replicated our findings of reduced semen quality among men whose mothers received fertility treatment (2). However, they argued that our findings may have been confounded by maternal body mass index. We did obtain information about maternal body mass index before a woman's pregnancy with the included son, and we did take that factor into account. It did not affect our findings, however; therefore, we did not adjust for maternal body mass index in the final analyses.
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ACKNOWLEDGMENTS
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Conflict of interest: none declared.
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References
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- Ramlau-Hansen CH, Thulstrup AM, Bonde JP, et al. Parental infertility and semen quality in male offspring: a follow-up study. Am J Epidemiol (2007) 166:568–70.[Abstract/Free Full Text]
- Jensen TK, Jørgensen N, Asklund C, et al. Fertility treatment and reproductive health of male offspring: a study of 1,925 young men from the general population. Am J Epidemiol (2007) 165:583–90.[Abstract/Free Full Text]

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