TABLE 2. Observed and expected* numbers of deaths, standardized mortality ratios, and 95% confidence intervals for women who received cosmetic breast implants, Ontario and Quebec, Canada, 1974–1997
Cause of death
|
ICD-9 codes
|
Observed
|
Expected
|
SMR
|
95% CI
|
|
| All causes |
|
480 |
648.8 |
0.74 |
0.68, 0.81 |
| Infectious diseases |
1–139 |
8 |
8.4 |
0.96 |
0.41, 1.88 |
| Endocrine diseases |
240–279 |
4 |
18.3 |
0.22 |
0.06, 0.56 |
| Mental disorders |
290–319 |
4 |
4.5 |
0.89 |
0.24, 2.27 |
| Nervous system diseases |
320–389 |
5 |
18.2 |
0.27 |
0.09, 0.64 |
| Circulatory diseases |
390–459 |
75 |
137.6 |
0.55 |
0.43, 0.68 |
| Coronary heart |
410–414, 429.2 |
35 |
70.7 |
0.50 |
0.35, 0.69 |
| Cerebrovascular |
430–438 |
29 |
32.7 |
0.89 |
0.59, 1.28 |
| Respiratory diseases |
460–519 |
16 |
26.7 |
0.60 |
0.34, 0.97 |
| Digestive diseases |
520–579 |
12 |
22.9 |
0.52 |
0.27, 0.91 |
| Cancer |
140–208 (excluding 173) |
229 |
303.1 |
0.76 |
0.66, 0.86 |
| Breast |
174 |
37 |
82.6 |
0.45 |
0.32, 0.62 |
| Brain |
191 |
6 |
10.5 |
0.57 |
0.21, 1.25 |
| Genital |
179–184 |
24 |
33.1 |
0.72 |
0.46, 1.08 |
| Colorectal |
153–154 |
25 |
23.0 |
1.09 |
0.70, 1.61 |
| Bronchus and lung |
162.2–5, .8, .9 |
70 |
62.3 |
1.12 |
0.88, 1.42 |
| Injuries |
800–999 |
113 |
82.4 |
1.37 |
1.13, 1.65 |
| Suicide |
950–959 |
58 |
33.5 |
1.73 |
1.31, 2.24 |
| Other |
800–949, 960–999 |
55 |
48.9 |
1.13 |
0.85, 1.47 |
Other deaths
|
Those not included above
|
14
|
26.7
|
0.52
|
0.29, 0.88
|
|
* Person-years of follow-up and deaths were accrued beginning 1 year after surgery; expected numbers of deaths were calculated by multiplying age, period of surgery, and cause-specific female mortality rates for Ontario and Quebec by the corresponding number of person-years of follow-up observed in the cohort.
ICD-9, International Classification of Diseases, Ninth Revision; SMR, standardized mortality ratio; CI, confidence interval.
