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Am J Epidemiol 2003; 158:825.
Copyright © 2003 by Johns Hopkins Bloomberg School of Public Health

LETTERS TO THE EDITOR

RE: "ABORTION, CHANGED PATERNITY, AND RISK OF PREECLAMPSIA IN NULLIPAROUS WOMEN"

Olga Basso

Danish Epidemiology Science Centre, Institute of Epidemiology and Social Medicine, University of Aarhus, DK 8000 Århus, Denmark

I read with interest the recent paper by Saftlas et al. (1) on abortion, changed paternity, and risk of preeclampsia in nulliparous women. In a paper from our group (2) that was referred to in their Discussion, we did not find any effect of change in paternity on preeclampsia in the second birth after adjustment for the interpregnancy interval, as it is correctly pointed out. However, Saftlas et al. state that we did not take abortion history into consideration, which, in the case of our paper, is not entirely true. We had only registry information on abortions, spontaneous or induced, and we checked whether considering in the analysis abortions occurring between the first and second birth changed our estimates. This is reported in the Results section (2, p. 627). Admittedly, our information on abortions might not have been of the best possible quality and we did not know the exact time of abortion, but we did not find any evidence that a history of one previous abortion (spontaneous or induced) was protective of preeclampsia, and adjusting for history of abortion did not change our estimates.

REFERENCES

  1. Saftlas AF, Levine RJ, Klebanoff MA, et al. Abortion, changed paternity, and risk of preeclampsia in nulliparous women. Am J Epidemiol 2003;157:1108–14.[Abstract/Free Full Text]
  2. Basso O, Christensen K, Olsen J. Higher risk of pre-eclampsia after change of partner. An effect of longer interpregnancy intervals? Epidemiology 2001;12:624–9.[CrossRef][Web of Science][Medline]

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This Article
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