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American Journal of Epidemiology Advance Access originally published online on March 30, 2009
American Journal of Epidemiology 2009 169(10):1278-1279; doi:10.1093/aje/kwp051
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American Journal of Epidemiology © The Author 2009. Published by the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org.

LETTERS TO THE EDITOR

Re: "NQO1 POLYMORPHISMS AND DE NOVO CHILDHOOD LEUKEMIA: A HUGE REVIEW AND META-ANALYSIS"

Marina Lanciotti and Carlo Dufour

Hematology Unit, G. Gaslini Children's Hospital, 16148 Genova, Italy

(e-mail: marinalanciotti@ospedale-gaslini.ge.it)

The first 10% of the full text of this article appears below.

After having read with great interest the Human Genome Epidemiology review recently published by Guha et al. (1), we would like to comment and raise some concerns.

The authors identified 7 case-control studies (2–8) investigating the association between NAD(P)H:quinone oxidoreductase 1 (NQO1) polymorphisms and childhood leukemia and presented results from a meta-analysis showing that the presence of an NQO1*2 . . . [Full Text of this Article]


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