American Journal of Epidemiology Advance Access originally published online on March 30, 2009
American Journal of Epidemiology 2009 169(10):1278-1279; doi:10.1093/aje/kwp051
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American Journal of Epidemiology © The Author 2009. Published by the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org.
LETTERS TO THE EDITOR |
Re: "NQO1 POLYMORPHISMS AND DE NOVO CHILDHOOD LEUKEMIA: A HUGE REVIEW AND META-ANALYSIS"
Hematology Unit, G. Gaslini Children's Hospital, 16148 Genova, Italy
(e-mail: marinalanciotti@ospedale-gaslini.ge.it)
| The first 10% of the full text of this article appears below. |
After having read with great interest the Human Genome Epidemiology review recently published by Guha et al. (1), we would like to comment and raise some concerns.
The authors identified 7 case-control studies (2–8) investigating the association between NAD(P)H:quinone oxidoreductase 1 (NQO1) polymorphisms and childhood leukemia and presented results from a meta-analysis showing that the presence of an NQO1*2