American Journal of Epidemiology Advance Access originally published online on October 16, 2006
American Journal of Epidemiology 2006 164(11):1139-1140; doi:10.1093/aje/kwj360
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American Journal of Epidemiology Copyright © 2006 by the Johns Hopkins Bloomberg School of Public Health All rights reserved; printed in U.S.A.
LETTERS TO THE EDITOR |
THE FIRST TWO AUTHORS REPLY
1 Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA 02215
2 Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032
3 Department of Environmental Health, Harvard School of Public Health, Boston, MA 02215
(e-mail: mglymour@hsph.harvard.edu)
| The first 10% of the full text of this article appears below. |
We are grateful for Dr. Cologne's comments (1) on our paper (2). We agree that the implications of "baseline" adjustment depend on the timing of measurement of the baseline and its possible causal relations with other variables. In our paper on identifying determinants of change in a health outcome, we used the term "baseline" to refer to the first available measure of the health outcome of interest. In some studies, the earliest measure of