American Journal of Epidemiology Advance Access originally published online on September 12, 2006
American Journal of Epidemiology 2006 164(10):945-946; doi:10.1093/aje/kwj318
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American Journal of Epidemiology Copyright © 2006 by the Johns Hopkins Bloomberg School of Public Health All rights reserved; printed in U.S.A.
Invited Commentary |
Invited Commentary: Challenges of using Contact Data to Understand Acute Respiratory Disease Transmission
From the Fred Hutchinson Cancer Research Center and the University of Washington, Seattle, WA
Correspondence to Dr. M. Elizabeth Halloran, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, MS LE-400, Seattle, WA 98109 (e-mail: betz@scharp.org).
Received for publication April 7, 2006. Accepted for publication April 21, 2006.
| The first 10% of the full text of this article appears below. |
Wallinga et al. (1
) have done an excellent job of demonstrating how simple data can be used to improve our estimation of transmission parameters for infectious disease models. Their analysis involves several steps illustrating a unifying framework, from collecting data on social contacts to model-fitting with relevant infectious disease data. First, there is estimation of the contact matrix from age-specific data on conversations. Second, assumptions are made to estimate the age-specific transmission parameters of a particular transmission model. Third, comparison is made with infectious disease outcome data for goodness of fit and model
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