American Journal of Epidemiology Copyright © 2006 by the Johns Hopkins Bloomberg School of Public Health All rights reserved; printed in U.S.A.
Letter to the Editor |
RE: "ASSOCIATIONS BETWEEN BREAST CANCER RISK AND THE CATALASE GENOTYPE, FRUIT AND VEGETABLE CONSUMPTION, AND SUPPLEMENT USE"
1 Unité 780 (Epidemiology and Biostatistics), Institut National de la Santé et de la Recherche Médicale, 94807 Villejuif, France
2 Institut Federatif de Recherche 69, Faculté de Médicine, Université de Paris-Sud, 94807 Villejuif, France
3 Laboratory of Respiratory Biology, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709
(e-mail: nadif@vjf.inserm.fr)
| The first 10% of the full text of this article appears below. |
We read with interest the paper by Ahn et al. (1
) on breast cancer. They reported a protective role of the catalase (CAT) 262 CC genotype that was enhanced by high intake of fruit, a source of antioxidants. This result is of potentially great importance, as catalase is a primary defense against oxidative stress, which could play a role in a variety of diseases.