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Am J Epidemiol 2004; 159:718-720.
Copyright © 2004 by the Johns Hopkins Bloomberg School of Public Health

LETTERS TO THE EDITOR

TWO AUTHORS REPLY

Moran Ki1,2 and Taesung Park3

1 Department of Preventive Medicine, Eulji University School of Medicine, Jung-gu, Taejon 301-726, Korea
2 Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI 48109
3 Department of Statistics, Seoul National University, Seoul 151-747, Korea

The first 10% of the full text of this article appears below.

We appreciate Dr. Farrington’s letter (1) and his interest in our paper (2). Dr. Farrington raised quite an important fundamental issue regarding the case-crossover design. The case-crossover design compares the probability of exposure between the control period and the hazard period (figure 1). If the probability of exposure is time dependent, the control period and the hazard period cannot be comparable, and the analysis . . . [Full Text of this Article]

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