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Am J Epidemiol 2004; 159:124-126.
Copyright © 2004 by the Johns Hopkins Bloomberg School of Public Health

ORIGINAL CONTRIBUTIONS

Invited Commentary: Uterine Leiomyomata—We Know So Little but Could Learn So Much

Donna Day Baird 

From the Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC.

Received for publication September 15, 2003; accepted for publication October 13, 2003.

The first 150 words of the full text of this article appear below.


   INTRODUCTION
 
Uterine leiomyomata, commonly called fibroids, are the leading cause of hysterectomy in the United States (1), yet as of a decade ago, there had been virtually no US study of this condition. Earlier studies in Italy (2) and Britain (3) had included only surgical cases, a highly selected case sample since many women with fibroids do not elect to have surgery. Thus, it is not surprising that there are few clearly established risk factors for fibroids. The new report from the Black Women’s Health Study is an important contribution (4), complementing the previous reports from the Nurses’ Health Study (5–7), which included mostly White women.

The clearly established risk factors are age (increasing risk with increasing premenopausal age), menopause (risk decreases with menopause), and African-American ethnicity (higher risk compared with that of non-Hispanic Whites). There is still no . . . [Full Text of this Article]

Age of menarche
Parity
Hormonal contraception
Future research strategies

   ACKNOWLEDGMENTS
 

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