Am J Epidemiol 2003; 158:22-24.
Copyright © 2003 by Johns
Hopkins Bloomberg School of Public Health
PRACTICE OF EPIDEMIOLOGY |
Invited Commentary: OPEN Questions
1 Department of Nutrition, Harvard School of Public Health, Boston, MA.
2 Department of Epidemiology, Harvard School of Public Health, Boston, MA.
3 The Channing Laboratory, Department of Medicine, Harvard Medical School, Boston, MA.
Received for publication March 14, 2003; accepted for publication March 20, 2003.
Abbreviations: Abbreviation: OPEN, Observing Protein and Energy Nutrition.
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INTRODUCTION |
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The papers by Subar et al. (1) and Kipnis et al. (2) in this issue of the Journal provide a unique set of data and a useful contribution to nutritional epidemiology. The Observing Protein and Energy Nutrition (OPEN) Study they report on was based on a reasonable sample of participants, had a remarkably high completion rate, and is the largest known study to use doubly labeled water as the standard for comparison. In addition, the measurements of doubly labeled water, which can be highly error prone (3), appear to have been made with a high degree of technical precision. The study also has several limitations inherent to using this approach, including that it enabled evaluation of only total energy and one specific nutrient, protein. Furthermore, the results cannot be readily generalized to other food frequency questionnaires because the values for total energy intake estimated
Effects of adjusting for energy intake
Correlated errors
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Related articles in Am. J. Epidemiol.:
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Am. J. Epidemiol. 2003 158: 1-13.[Abstract] [FREE Full Text] - Structure of Dietary Measurement Error: Results of the OPEN Biomarker Study
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Am. J. Epidemiol. 2003 158: 25-26.[Extract] [FREE Full Text]
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