Skip Navigation



American Journal of Epidemiology Advance Access published online on November 6, 2009
American Journal of Epidemiology, doi:10.1093/aje/kwp321
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Bodelon, C.
Right arrow Articles by Weiss, N. S.
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bodelon, C.
Right arrow Articles by Weiss, N. S.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

American Journal of Epidemiology © The Author 2009. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org.

Original Contribution

Use of Nonsteroidal Antiinflammatory Drugs and Risk of Endometrial Cancer

Clara Bodelon*, Jennifer A. Doherty, Chu Chen, Mary Anne Rossing and Noel S. Weiss

* Correspondence to Dr. Clara Bodelon, Department of Epidemiology, Box 357236, School of Public Health, University of Washington, 1959 Northeast Pacific Street, Seattle, WA 98195-7236 (e-mail: bodelon{at}u.washington.edu).

Received for publication June 17, 2009. Accepted for publication September 11, 2009.

Results of 3 previous studies suggest that use of aspirin is related to a reduced risk of endometrial cancer, at least in obese women (body mass index, ≥30 kg/m2). Using data obtained in a population-based, case-control study in western Washington State, the authors examined this question. Between 2003 and 2005, 410 women diagnosed with invasive endometrial cancer and 356 controls were interviewed regarding the use of aspirin and other nonsteroidal antiinflammatory drugs (NSAIDs). A history of use of NSAIDs was not associated with the risk of endometrial cancer (odds ratio = 1.04, 95% confidence interval: 0.76, 1.42). The lack of association was also present specifically for use of aspirin (odds ratio = 1.06, 95% confidence interval: 0.73, 1.53). NSAID use was unrelated to risk of endometrial cancer in both obese and nonobese women. Results from this study suggest that the use of aspirin or other NSAIDs has little or no influence on the risk of endometrial cancer.

anti-inflammatory agents, non-steroidal; aspirin; body mass index; endometrial neoplasms

Abbreviations: CI, confidence interval; NSAID, nonsteroidal antiinflammatory drug; OR, odds ratio


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.