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American Journal of Epidemiology Advance Access published online on December 3, 2007

American Journal of Epidemiology, doi:10.1093/aje/kwm337
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American Journal of Epidemiology © The Author 2007. Published by the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org.

Original Contributions

Age at Retirement and Mortality in a General Population Sample

The Greek EPIC Study

Christina Bamia1, Antonia Trichopoulou1,2 and Dimitrios Trichopoulos2,3

1 Department of Hygiene and Epidemiology, University of Athens, Medical School, Athens, Greece
2 Hellenic Health Foundation, Athens, Greece
3 Department of Epidemiology, Harvard School of Public Health, Boston, MA

Correspondence to Dr. Christina Bamia, Department of Hygiene and Epidemiology, University of Athens, Medical School, 75 Mikras Asias Street, 115 27 Athens, Greece (e-mail: cbamia{at}nut.uoa.gr).

Received for publication July 19, 2007. Accepted for publication October 23, 2007.

Investigation of the health effects of retirement and age at retirement is limited, but the issue is particularly important given the pressure for an increase in the retirement age in Europe. In the Greek segment of the European Investigation into Cancer and Nutrition study, 16,827 men and women enrolled from 1994 to 1999 were either gainfully employed or had retired from such employment at enrollment; had not previously been diagnosed with stroke, cancer, coronary heart disease, or diabetes mellitus; and had complete information on important covariates and documented survival status as of July 2006. All-cause and cause-specific mortality in relation to employment status and age at retirement (among retirees) was analyzed through Cox regression models, controlling for potential confounders. In comparison to subjects still employed, retirees had a 51% increase in all-cause mortality (95% confidence interval: 16, 98). Among retirees, a 5-year increase in age at retirement was associated with a 10% decrease in mortality (95% confidence interval: 4, 15). Findings were more evident for cardiovascular than for cancer mortality, whereas, for injury mortality, there was no evidence of association. Results indicate that early retirement may be a risk factor for all-cause and cardiovascular mortality in apparently healthy persons.

cohort studies; retirement; survival

Abbreviations: EPIC, European Prospective Investigation into Cancer and Nutrition


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E. C. Alexopoulos
RE: "AGE AT RETIREMENT AND MORTALITY IN A GENERAL POPULATION SAMPLE: THE GREEK EPIC STUDY"
Am. J. Epidemiol., October 15, 2008; 168(8): 974 - 975.
[Full Text] [PDF]


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Am J EpidemiolHome page
C. Bamia, A. Trichopoulou, and D. Trichopoulos
THE AUTHORS REPLY
Am. J. Epidemiol., October 15, 2008; 168(8): 975 - 975.
[Full Text] [PDF]



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