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American Journal of Epidemiology Vol. 99, No. 4: 281-290
Copyright © 1974 by The Johns Hopkins University School of Hygiene and Public Health


other

ACUTE DIARRHEA ON AN APACHE INDIAN RESERVATION1

WILLIAM E. WOODWARD2,3, NORBERT HIRSCHHORN2, R. BRADLEY SACK2,4, RICHARD A. CASH2, INEZ BROWNLEE4, GRACE H. CHICKADONZ5, LOIS K. EVANS5, RICHARD H. SHEPARD2 and R. CRAIG WOODWARD2

2Departments of Medicine, Johns Hopkins University School of Medicine and Baltimore City Hospitals Baltimore, Maryland
4Department of Medicine, University of Oregon Portland, Oregon
5Georgetown University School of Nursing Washington, D.C.

3Reprint requests to Dr.W.E.Woodeard, University of Maryland School of Medicine, Department of Medicine, Infection Disease Division,29 S.Greene Street, Baltimore, Maryland21201

A comprehensive study of the causes and treatment of acute "summer diarrhea" on the Fort Apache Reservation found that the peak incidence was in children under age two of whom two-fifths were affected at least once, and one-quarter of all children required hospitalization. Thirty-five per cent of rectal swab cultures yielded a recognized pathogen, primarily Shigella species. In spite of liberal antimicrobial usage on the reservation no Shigella isolate showed multiple drug resistance. Conversely, one-third of the isolates of enteropathogenic Escherichia coli serotypes were multiply resistant. S. flexneri predominated over S. sonnei by 4: 1. A significant correlation between poor home sanitation and the isolation of S. flexneri was found. The diarrheal attack rate rose simultaneously with rainfall, temperature and bacterial contamination of water sources. Diarrhea continues to be a serious burden to Apache people.

diarrhea; Escherichia coli infections; Indian, North American; sanitation; Shigella


1This study was supported by National Institute of Arthritis, Metabolism, and Digestive Diseases Contract 71–2260


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