Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by TOP, F. H.
Right arrow Articles by BUESCHER, E. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by TOP, F. H., JR
Right arrow Articles by BUESCHER, E. L.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

American Journal of Epidemiology Vol. 94, No. 2: 142-146
Copyright © 1971 by The Johns Hopkins University School of Hygiene and Public Health

other

CONTROL OF RESPIRATORY DISEASE IN RECRUITS WITH TYPES 4 AND 7 ADENOVIRUS VACCINES

FRANKLIN H. TOP, JR, BURTON A. DUDDING, PHILIP K. RUSSELL and EDWARD L. BUESCHER1 2

1Department of Virus Diseases, Division of Communicable Diseases and Immunology, Walter Reed Army Institute of Research Washington, D. C. 20012

Top., F. H., Jr., B. A. Dudding, P. K. Russell and E. L. Buescher (Walter Reed Army Institute of Research, Wash., D.C. 20012). Control of respiratory disease in recruits with types 4 and 7 adenovirus vaccines. Amer J Epidem 94: 142–146, 1971.—Simultaneous immunization of recruits in a basic combat training brigade with live adenovirus type 7 and type 4 (ADV-7, ADV-4) vaccines during an outbreak of acute respiratory disease (ARD) caused by both adenovirus types led to 95% suppression of ADV-7 associated ARD and 50% reduction in total ARD hospitalizations as compared with a brigade immunized with ADV-4 vaccine alone. A small excess of ADV-4 associated ARD hospitalizations which occurred in the study brigade may have been due in part to the relatively low potency of ADV-4 vaccine used. The combined use of ADV-4 and ADV-7 vaccines proved to be a safe and effective means of controlling ARD in a military trainee population.

adenovirus; recruits; respiratory diseases; vaccines

2This study was undertaken with the concurrence of the Surgeon General of the Army, and the Army Investigational Drug Review Board, the Vaccine Development Branch. National Institutes of Allergy and Infectious Diseases, and with the collaboration of the Surgeon and Training Command, Fort Dix, N.J.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J. Virol.Home page
M. J. McConnell, X. Danthinne, and M. J. Imperiale
Characterization of a permissive epitope insertion site in adenovirus hexon.
J. Virol., June 1, 2006; 80(11): 5361 - 5370.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
M. J. McConnell, P. C. Hanna, and M. J. Imperiale
Cytokine Response and Survival of Mice Immunized with an Adenovirus Expressing Bacillus anthracis Protective Antigen Domain 4
Infect. Immun., February 1, 2006; 74(2): 1009 - 1015.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.