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American Journal of Epidemiology Vol. 90, No. 3: 236-243
Copyright © 1969 by The Johns Hopkins University School of Hygiene and Public Health

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A COMPARISON BETWEEN THE CHARACTERISTICS OF JAMAICAN ADULTS WITH NORMAL HEMOGLOBIN AND THOSE WITH SICKLE CELL TRAIT1

M. T. ASHCROFT, W. E. MIALL and P. F. MILNER

Ashcroft, M. T. (Medical Research Council Epidemiological Research Unit, University of the West Indies, Kingston 7, Jamaica), W. E Miall and P. F. Milner. A comparison between the characteristics of Jamaican adults with normal hemoglobin and those with sickle cell trait. Amer. J. Epid., 1969, 90: 236–243.—In surveys of representative samples of Jamaicans aged 35–64 years living in rural and suburban communities, no significant differences in heights, weights, hema-tological indices, cardiothoracic ratios, blood pressures, glycosuria, proteinuria, parity or electrocardiographic abnormalities were apparent between 167 subjects with the sickle cell trait, AS, and 1, 282 subjects with normal hemoglobin, AA. Older women with the trait had a significantly higher prevalence of bacte-riuria without other evidence of urinary tract pathology. The findings suggest that the trait is not appreciably associated with chronic disease.

anemia, sickle cell; bacteriuria; blood pressure; epidemiology; hemoglobin; sickle cell trait

1From the Medical Research Council Epidemiological Research Unit and the Department of Haematology, University of the West Indies, Kingston 7, Jamaica.


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