Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by DRESCHER, J.
Right arrow Articles by TYRRELL, D. A. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by DRESCHER, J.
Right arrow Articles by TYRRELL, D. A. J.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

American Journal of Epidemiology Vol. 89, No. 1: 98-109
Copyright © 1969 by The Johns Hopkins University School of Hygiene and Public Health

research-article

THE TITRATION OF RHINOVIRUSES AND OF ANTIBODIES AGAINST THEM BY MEANS OF THE PHOTOMETRIC HEMAGGREGATION-INHIBITION TEST

JOACHIM DRESCHER 1 and DAVID A. J. TYRRELL 2

Institute of Microbiology, Medizinische Hochschule Hannover, Hannover-Kleefeld Bissendorferstrasse 9, Germany

The novel technique for the titration of rhinoviruses and of antibodies against them described in this paper is based on the finding that rhinovirus suspensions inhibit the aggregation of trypsin-treated human erythrocytes, suspended in an albumin containing glucose solution of low ionic strength at low pH, and that the hemag-gregation inhibiting activity of the virus suspensions is specifically bound by the addition of homologous antibody. This paper gives a detailed description of the conduct of tests. Furthermore, the results of testing rhinovirus suspensions and antisera comparatively both by hemaggregation inhibition test and by conventional techniques are presented.

antibodies; hemagglutination tests; hemaggregation; immunity; rhinovirus; sero-diagnosis

1Present address: Virus Department, Institute of Microbiology, Medizinische Hochschule Hannover, Hannover-Kleefeld, Bissendorferstraße 9, Germany.

2Present address: Clinical Research Centre Laboratories, National Institute for Medical Research, Mill Hill, London, N.W. 7, England.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.