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American Journal of Epidemiology Vol. 88, No. 1: 25-32
Copyright © 1968 by The Johns Hopkins University School of Hygiene and Public Health


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CHRONIC DISEASE IN FORMER COLLEGE STUDENTS. VIII. CHARACTERISTICS IN YOUTH PREDISPOSING TO HYPERTENSION IN LATER YEARS1

RALPH S. PAFFENBARGER, JR., MELVYN C. THORNE and ALVIN L. WING

Paffenbarger, R. S., Jr., M, C. Thome and A. L Wing (National Heart Institute and Harvard University School of Public Health, Boston, Mass.) Chronic disease in former college students. VIII. Characteristics in youth predisposing to hypertension in later years. Amer. J. Epid., 1968, 88; 25–32.-Doctor—diagnosed high blood pressure was reported by 671 (8.7%) of 7, 685 men who had attended the University of Pennsylvania, 1931–1940, and completed a self-administered questionnaire in 1962. The mean age of study subjects was 19 years at college case-taking, 36 years at recognition of hypertension, and 46 years at questionnaire response. Examination of college medical and athletic records of these former students revealed six characteristics in youth precursive of hypertension in middle life; higher levels of blood pressure, faster pulse rate, greater ponderosity, history of parental hypertension, flrst-bom status, and less participation in sports or exercise. Correlations with hypertension were amplified when these precursors occurred in combinations.


1From the Field Epidemiological Research Section, National Heart Institute, U.S. Public Health Service and the Department of Epidemiology, Harvard University School of Public Health. Address reprint requests to Dr. Paffenbarger at 1 Shattuck Street, Boston, Mass. 02115.


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