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American Journal of Epidemiology Vol. 87, No. 3: 599-608
Copyright © 1968 by The Johns Hopkins University School of Hygiene and Public Health

research-article

AN OUTBREAK OF TYPE 25 ECHOVIRUS INFECTION WITH EXANTHEM IN AN INFANT HOME NEAR TOKYO1

YASUO MORITSUGU3, KEIJI SAWADA3, MASAYUKI HINOHARA3, KOKO TSUCHIYA2, ISAMU TAGAYA2, MUNEHIRO HIRAYAMA4 and TAKESHI FUTAKI3

2Department of Enteroviruses, National Institute of Health 10-35 2-chome, Kamiosaki, Shinagawa-ku, Tokyo, Japan
3Hachioji Infant Home, Hachioji, Tokyo, Japan
4Department of Pediatrics, University of Tokyo Tokyo, Japan

Moritsugu, Y., K. Sawada, M. Hinohara, K. Tsuchiya, I. Tagaya, M. Hirayama and T. FutakJ (Dept. of Enteroviruses, Nat. mst. of Health, Tokyo). An outbreak of type 25 echovirus infection with exanthem in an infant home near Tokyo. Amer. J. Epid., 1968, 87: 599–608.—An outbreak of echovirus 25 infection associated with fever, upper respiratory symptoms and rashes was observed in infants in an infant home near Tokyo in June 1963. Out of 59 infants 51 showed certain symptoms. Fever was observed in 81 per cent, upper respiratory symptoms in 84 per cent and exanthem in 32 percent. Symptoms were in general mild. The exanthem consisted of macules of 2 to 3 mm, maculopapules in some cases, and appeared mostly on the face and extremities. Vlrologk, serologk and epidemiobgic evidence was obtained concerning the etioiogtc role of echovirus 25 in thb outbreak. Echovirus 25 isolated from dinical specimens was serologfcally quite similar to, but not identical with, the prototype strain, JV-4.

1This work was supported in part by a research grant from the Ministry of Education of Japan.


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