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American Journal of Epidemiology Advance Access originally published online on August 12, 2008
American Journal of Epidemiology 2008 168(8):872-875; doi:10.1093/aje/kwn192
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American Journal of Epidemiology © The Author 2008. Published by the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org.

Invited Commentary

Invited Commentary: Never, or Hardly Ever? It Could Make a Difference

Arthur L. Klatsky

Correspondence to Dr. Arthur L. Klatsky, Kaiser Permanente Medical Center, 280 West MacArthur Boulevard, Oakland, CA 94611 (e-mail: hartmavn{at}pacbell.net, arthur.klatsky{at}kp.org).

Received for publication April 6, 2008. Accepted for publication April 23, 2008.

A paper showing that about one half of persons stating lifelong alcohol abstinence had previously reported drinking (Am J Epidemiol 2008;168(8):866—871) reopens debate about the validity of this frequently used referent group in alcohol-health studies. Misclassification of lifelong abstainers could result in underestimation of harmful effects of heavy drinking and overestimation of benefits of lighter drinking. Imprecise and unreliable ascertainment of alcohol intake is the rule in the area of alcohol epidemiology research. However, inaccurate ascertainment of past infrequent drinking may have less effect upon outcome estimates than the consequences of other measurement errors such as underreporting of intake. Communication about alcohol-health relations would be improved if all research reports explicitly described queries and methods by which alcohol intake was categorized and if limitations were always frankly acknowledged.

alcohol drinking; control groups; data collection; longitudinal studies; reproducibility of results


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