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American Journal of Epidemiology Advance Access originally published online on June 18, 2008
American Journal of Epidemiology 2008 168(6):587-589; doi:10.1093/aje/kwn161
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American Journal of Epidemiology © The Author 2008. Published by the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org.

Invited Commentary

Invited Commentary: Physical Activity and Vitamin D

Fraser Birrell1,2,3 and Roger M. Francis1,3

1 Musculoskeletal Research Group, Newcastle University, Newcastle upon Tyne, United Kingdom
2 Department of Rheumatology, Northumbria Healthcare National Health Service Foundation Trust, Newcastle upon Tyne, United Kingdom
3 Musculoskeletal Unit, Freeman Hospital, Newcastle upon Tyne, United Kingdom

Correspondence to Dr. Fraser Birrell, Musculoskeletal Research Group, Newcastle University, Fourth Floor, Catherine Cookson Building, Framlington Place, Newcastle upon Tyne NE2 4HH, United Kingdom (e-mail: Fraser.Birrell{at}ncl.ac.uk).

Received for publication April 10, 2008. Accepted for publication April 14, 2008.

Exercise and vitamin D are both important for musculoskeletal health. In this issue of the Journal, Scragg and Camargo (Am J Epidemiol 2008;168:577–86) provide a new analysis of relatively old data on physical activity and vitamin D from the Third National Health and Nutrition Examination Survey (1988–1994). This commentary considers the methodological strengths and weaknesses of the study and concludes that the findings are as robust as could reasonably be expected from a cross-sectional design. Consideration is given to whether outdoor exercise is the cause of higher vitamin D levels and, if so, whether mortality gains may accrue from more widespread participation. A note of caution is sounded, given the disappointing results on studies of the prevention of falls and fractures with vitamin D supplementation in community-dwelling populations. However, this is an important observation, and more epidemiologic studies are needed, preferably including care home residents. Applied researchers should consider further studies of vitamin D supplementation in older people, possibly combined with an exercise intervention. Public health professionals and practicing clinicians should recognize that there is a rationale for recommending outdoor exercise, and they should seek to improve universal accessibility.

exercise; vitamin D


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Related articles in Am. J. Epidemiol.:

Frequency of Leisure-Time Physical Activity and Serum 25-Hydroxyvitamin D Levels in the US Population: Results from the Third National Health and Nutrition Examination Survey
Robert Scragg and Carlos A. Camargo, Jr.
Am. J. Epidemiol. 2008 168: 577-586. [Abstract] [Full Text]  



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R. Scragg and C. A. Camargo Jr
Scragg and Camargo Respond to "Physical Activity and Vitamin D"
Am. J. Epidemiol., September 15, 2008; 168(6): 590 - 591.
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