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American Journal of Epidemiology Advance Access originally published online on June 7, 2007
American Journal of Epidemiology 2007 166(2):125-127; doi:10.1093/aje/kwm141
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American Journal of Epidemiology Published by the Johns Hopkins Bloomberg School of Public Health 2007.

Invited Commentary

Invited Commentary: Identifying Women with Hypertension during Pregnancy—Is High Specificity Sufficient?

William M. Callaghan

From the Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA

Correspondence to Dr. William M. Callaghan, Division of Reproductive Health, Centers for Disease Control and Prevention, 4770 Buford Highway, Mailstop K-23, Atlanta, GA 30341 (e-mail: wcallaghan{at}cdc.gov).

Received for publication August 6, 2006. Accepted for publication August 9, 2006.

Hypertensive complications of pregnancy contribute to the burden of maternal morbidity and subsequently have an impact on neonatal morbidity and mortality. Although codes from the International Classification of Diseases should delineate the specific subtypes of pregnancy-related hypertension, how diagnoses are applied and how these codes are used in clinical settings are largely unknown. This commentary discusses the implications of using administrative codes to identify women with preeclampsia syndromes, especially when used to define outcomes or exposures for etiologic research.

hypertension; pregnancy; sensitivity and specificity; women

Abbreviations: ICD, International Classification of Diseases


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Related articles in Am. J. Epidemiol.:

Validity of Preeclampsia-related Diagnoses Recorded in a National Hospital Registry and in a Postpartum Interview of the Women
Åse K. Klemmensen, Sjurdur F. Olsen, Marie Louise Østerdal, and Ann Tabor
Am. J. Epidemiol. 2007 166: 117-124. [Abstract] [FREE Full Text]  



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M. Osterdal, A. Klemmensen, A Tabor, and S. Olsen
Osterdal et al. Respond to "Identifying Women with Hypertension during Pregnancy"
Am. J. Epidemiol., July 15, 2007; 166(2): 128 - 129.
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